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Various GLP-1RAs have been demonstrated to have significant benefits in in vitro and in vivo models of neurodegenerative diseases through modulating a variety of pathogenic mechanisms, including neuroinflammation, autophagy, mitochondrial dysfunction, and the abnormal phosphorylation of pathognomonic proteins

Dr Gregom Sng and Dr Chew Chun Yang from Parkway Shenton explain whos suitable, how these medications work, and what results to expect.

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FDA approval is anticipated in 2026, through the FDA's national priority voucher program, positioning Lilly to compete aggressively in the oral segment

Will Lilly take the top spot

A new Nature Medicine review by Daniel Drucker, a pioneer of this field | 12 comments on LinkedIn