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Given their ability to increase insulin release and enhance insulin sensitivity in peripheral tissues, these drugs were identified as, and remain a key therapy for type 2 diabetes

More than weight loss: GLP-1s reshape spending and self-control GLP-1 medications are doing more than supporting weight loss
66 Targeting multiple peptide hormone receptors with the same drug entity appears to be the most promising strategy, where additive, or even synergistic, benefits of simultaneously activating two receptor signalling pathways in bone can be fully realised
This led to their marketing for obesity and metabolic health
Historically, federal law has prevented Medicare plans from covering weight loss medications

Tirzepatide has not been studied in pregnant or breastfeeding women, and animal studies suggest potential fetal harm