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For women with pre-existing conditions such as PCOS, endometriosis, or thyroid disorders, it is particularly important to work closely with your healthcare provider to distinguish between expected improvements in cycle regularity and concerning changes that may require investigation

According to NICE guidance, Mounjaro is recommended for people with: BMI of at least 35 kg/m and at least one weight-related health condition, or BMI of at least 30 kg/m with type 2 diabetes NICE recommends Mounjaro be prescribed alongside a reduced-calorie diet and increased physical activity, with treatment reviewed after 12 months to assess effectiveness 6

Persistent symptoms despite 2 weeks of PPI therapy: If omeprazole or similar medications are not controlling your heartburn, your provider may want to perform an endoscopy or pH monitoring to evaluate for complications like Barrett esophagus or esophageal stricture

Zepbound may fit a weight-management goal

Study cohorts We designed five active-comparator, new-user cohort studies including patients with obesity and type 2 diabetes at elevated cardiovascular risk 46

The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication