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Results vary, as expected

3,249 patients were excluded due to missing demographics, age 40 years, missing demographics, prior use of any study drug, diagnosis of type 1 DM, retinal disorders classified based on the ICD categories (DR, retinal vascular occlusion, separation of retinal layers [including all types of retinal detachment and central serous retinopathy], degeneration of retina, chorioretinal inflammations, and other retinal disorders [including retinal hemorrhage, vitreous hemorrhage, retinal edema, etc.]), history of receiving vitreoretinal interventions (intravitreal injection, laser coagulation, and vitrectomy), no baseline glycosylated hemoglobin (HbA1c), or no follow-up data in the subsequent 6 months after being prescribed the medication, were excluded from this study

doi: 10.1371/journal.pone.0172604 122 GrabenhorstFRollsETParrisBAdSouzaAA

/ mice may partially explain this inhibition of chemokine and inflammatory factor secretion

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