retatrutide triple hormone receptor agonist metabolic Medscape | Retatrutide, Eli Lilly's first-in-class agonist, delivered meaningful weight loss at 80 weeks in all doses in the How Does Retatrutide Work? Triple
Description
Whilst thirst is not specifically listed as an adverse reaction in the Summary of Product Characteristics (SmPC), dehydration is recognised as a potential adverse effect, primarily related to gastrointestinal side effects
(2) reduce clearance rate due to slowed metabolism and renal filtration (131)
A21-4214, first approved 22 February 2021)
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The reasons are not fully understood, but they may involve the complex interplay between GLP-1 signaling and the cortical spreading depression that characterizes hemiplegic migraine
