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Report any unusual symptoms to your healthcare provider promptly

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In a study using cultured rat hippocampal neurons, pre-treatment of nerve cells with GLP-1 resulted in a weakened Ca 2+ response to glutamate and weakened membrane depolarization ( Effects on Parkinsons Disease Parkinsons disease (PD) is a chronic neurodegenerative disease that affects the central nervous system and the second most common neurodegenerative disease after AD (56)

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In addition, an inverse correlation between circulating free fatty acids and GLP-1 concentrations have been found in vivo and in vitro experiments, and systemic GLP-1 levels can be increased in obese patients after treatment with acipimox [94]

They have been implicated in promoting neuroprotection, improving neurological structure and functions, attenuating apoptosis, mitigating oxidative stress, and modulating neuroinflammation [11,12,13]