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Conclusions/interpretation A dose-dependent superiority on glycaemic efficacy and body weight reduction was evident with tirzepatide vs placebo, GLP-1 RAs and basal insulin
Amp-activated protein kinase plays a role in the control of food intake
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GLP-1R is a G-protein coupled receptor and is widely localized in astrocytes, neurons and endothelial cells [20,21,22]
It can cause dangerous blockages, be life-threatening, and may require surgery or urgent medical attention to correct
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