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These agents delay gastric emptying which makes patients feel fuller for longer

But as drugs like Ozempic and Wegovy move from specialist treatment to everyday use, a quieter health issue is emerging in parallel

Your body follows a circadian rhythm that influences gut microbiome , glucose metabolism, and the release of hormones involved in appetite regulation, including the GLP-1 hormone

And because it also slows digestion, Ozempic can affect how quickly and effectively your body absorbs other medications, too

Related to the anti-inflammatory role of GLP-1 RAs, it has been demonstrated that liraglutide, exendin-4, DA3-CH, DA5-CH, and DA-JC1 reduce the activation of microglia and astrocytes in the MPTP mouse model of PD [184,185,186,187,191]

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