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The 12 mg dose had higher gastrointestinal event rates and higher discontinuation due to adverse events than lower doses, emphasizing the need to balance efficacy with tolerability

If you have diabetes and are also taking insulin or sulfonylureas, be aware that dose adjustments may be needed to prevent hypoglycaemia

The results were provocative, weight loss with participants losing up to 28.7% of their total body weight over 68 weeks [33]

Additionally, semaglutide stimulates insulin release and enhances blood sugar control, further aiding in appetite regulation and reducing carbohydrate cravings