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Common Side Effects and How to Manage Them Potential side effects include: Nausea Constipation Abdominal pain Hypoglycemia (low blood sugar) Gastrointestinal discomfort Mitigate these side effects by: Hydrating adequately Gradually increasing dosage Taking medication consistently at the same time each week Regularly communicating with your healthcare provider Combining Semaglutide with Lifestyle Changes Semaglutide is most effective when combined with: Balanced Nutrition: Prioritize whole foods, lean proteins, vegetables, and fiber-rich grains

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After discontinuation, appetite often returns, while the body remains adapted to a lower calorie intake

Ann Pharmacother (2011) 45:85060