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It enhanced beta cell function, increasing both first- and second-phase insulin secretion compared with placebo, which means the pancreas was better able to respond to blood glucose
Cell Metab 32:379-390.e3
If you've maintained semaglutide for 16+ weeks without meaningful progress, genetic testing through PlexusDx can identify whether receptor-level factors explain your plateau
This transient effect should resolve within the first week
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