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Obesity induces metabolic disturbances in adipose tissue, influencing the release of hormones, adipokines, inflammatory cytokines, growth factors, enzymes, and free fatty acids [12]

Patients should never accelerate dose escalation without medical supervision, even if initial tolerance seems good

JCI Insight (2020)

This long-term use would put an enormous strain on the cost of health care for individuals, insurance companies and employer groups

These long-acting incretin receptor agonists have revolutionized the landscape of obesity and T2D research and are now being explored for other metabolic disorders, including non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD) [1]