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Spots may be evident on the face, chest or shoulders

In some cases, temporary discontinuation of GLP-1 therapy may be necessary until blood pressure stabilizes

While pancreatic -cells are the principal therapeutic target, GLP-1Rs are widely expressed in -cells, exocrine pancreas, intestinal mucosa, renal tubules, pulmonary epithelium, selected brain nuclei, and the cardiac sinoatrial node

Overall, these findings emphasize that while AAS is rare in PsA, it appears to be linked to structural damage and axial involvement, rather than to current inflammatory activity alone

The pain may intensify within hours, making even the slightest movement unbearable

Some patients adapt well once they see the pattern