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Comprehensive ePRO Portfolio: We have experience in supporting a wide range of ePRO measures to assess aspects of health important to patients with these diseases including: Health-related quality of life (HRQoL, e.g., SF-36, Impact of Weight on Quality of Life-Lite (IWQoL-Lite)(EQ-5D-5L), Food craving (e.g., Control of Eating Questionnaire (CoEQ)), Mental health (e.g., Columbia-Suicide Severity Rating Scale (C-SSRS), Patient Health Questionnaire-9 (PHQ-9)) and other measures such as the Patient Global Impression of Severity/Change (PCIS/C)

Finally, our in vitro results indicated that liraglutide may attenuate cartilage degradation through an anti-catabolic effect at both at the protein and gene expression levels

Previously, he was taking metformin, insulin, and Jardiance each day

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While GLP-1 medications are not recommended solely for alcohol cravings outside research settings, if prescribed for approved indications, patients should be counseled on the limited evidence and monitored appropriately