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Patients will typically start at the lowest dose (0.8 mg) and gradually work their way up to the highest dose they can tolerate (up to 17.2 mg)

Deliver the medication: Slowly push the plunger to inject the entire amount of medication

[77] and hrstrm et al., pasireotide prevented hypoglycemic episodes with minimal hyperglycemic effects [78]

These two papers established retatrutide as the leading Phase-2-stage candidate in the multi-agonist metabolic-pharmacology class as of the 2023-2024 publication window

In the era of new anti-diabetic options, their early use should be considered to reduce the demand for insulin and limit insulin resistance induced by glucocorticoids

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