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In macrophages, a decrease in extracellular osmolarity (hypotonic challenge) and the subsequent regulatory volume decrease (RVD) phenomenon also leads to NLRP3 inflammasome activation 7,8
Thannickal VJ
EMBO Mol Med 2019 Jun;11(6):e9856
Knocking out genes related to mitochondrial fission promotes NLRP3-dependent caspase-1 activation and IL-1 secretion
From antiquity, it has been used to treat a variety of diseases (Ali et al
Tumor metabolism aiming Cu(2-x)S nanoagents mediate photothermal-derived cuproptosis and immune activation
