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A growing share of employers are rethinking coverage of the weight-loss drugs as costs rise and early expectations of lower obesity rates and surgical needs have yet to surface in claims data.

(Bifidobacterium lactis BS01, Bifidobacterium breve BR03, Lactobacillus acidophilus LA02, Lactobacillus plantarum LP09, Lactobacillus rhamnosus LR06, Lactobacillus casei LC03, Bifidobacterium bifidum BB01, Streptococcus thermophilus YO8, Lactobacillus plantarum LP01, Lactobacillus rhamnosus LR05, Lactobacillus rhamnosus GG, Bifidobacterium longum BL03, Lactobacillus reuteri LRE02, Lactobacillus salivarius subsp. salivarius CRL1328, Bifidobacterium lactis BA05)

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Our findings thus reveal the source of the longevity signalling in response to germline removal, highlighting the stem cell niche as a critical signalling hub in ageing.