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Initial therapy with the combination of JANUVIA and metformin provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo, to metformin alone, and to JANUVIA alone (Table 8, Figure 1)

Efficacy and safety of Once-Weekly dulaglutide versus insulin glargine in patients with type 2 diabetes on Metformin and glimepiride (AWARD-2)

Bays, A

Food significantly reduces its absorption and effectiveness

Work closely with your healthcare provider to monitor tolerability

To probe whether semaglutide exerts a direct adverse vascular effect, a separate randomized controlled trial specifically investigated its impact on retinal physiology