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Similarly, Rybelsus has relatively low oral bioavailability and requires very specific conditions for absorption: it must be taken with no more than 120ml of water, on an empty stomach, with no food, drink, or other oral medications for at least 30 minutes afterwards

The PK properties of OW semaglutide in healthy Chinese subjects in this trial appeared similar to the PK properties observed in other clinical pharmacology trials with OW semaglutide [23, 28, 29]

For these reasons, longer-term trials are necessary to clarify this relation with a more uniform and bigger sample

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