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DiMarchi transformed thinking about the hormones this class oftherapies should mimic, a critical part of their efficacy. Despite critics who doubted obesity was a disease at all, they relentlessly pursued this use case, well beyond being the first 2 to patent it
So while microdosing may not deliver the same magnitude of effect, it can still work when the outcome aligns with the patients specific goals, says Dr

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial Lau DCW, Erichsen L, Francisco-Ziller N, et al
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Saxenda is specifically approved for chronic weight management alongside diet and exercise

[DOI] [PubMed] [Google Scholar] 103.Knapen L.M., de Jong R.G.P.J., Driessen J.H.M., Keulemans Y.C., van Erp N.P., De Bruin M.L., Leufkens H.G.M., Croes S., de Vries F