glp-1 news today insurers coverage Department of Insurance Issues First-Ever Report Massachusetts cuts GLP-1 coverage for

Description

Mean change in HbA1c to end of treatment according to baseline eGFR (truncated between 5th and 95th percentile) in SUSTAIN 46, and 10, and PIONEER 5 and 6

Patients see maximum results when combining GLP1 with lifestyle improvements

Discussion While GLP-1 RAs are powerful anti-obesity medications (AOMs), they do raise some serious concerns most notably, up to 40% of the profound weight loss induced by these agents can be due to loss of lean mass 3,4,5 and prior studies have shown that a significant portion of this lean mass is muscle 33,34,35

As an added advantage, GLP-1s are not themselves addictive and don't trigger withdrawal

Moreover, increasing evidence postulates a production and paracrine role for small amounts of bioactive GLP-1 produced by pancreatic -cells (Nie et al