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Another factor that may contribute for non-responders relates to the causes of obesity itself

It is important to note that while subcutaneous administration means absorption is not affected by altered gastrointestinal anatomy, patients may experience more pronounced gastrointestinal side effects

A synaptic amplifier of hunger for regaining body weight in the hypothalamus

Not for human consumption, injection, or therapeutic use

Additionally, patients with diabetic retinopathy should proceed with caution, particularly when using subcutaneous semaglutide, as some trials have reported a higher incidence of retinopathy-related complications