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Description
These are manageable with dose titration, but they drive roughly half of early discontinuations

Constipation and GI slowdown Delayed gastric emptying is a feature of all GLP-1 agonists, and retatrutide is no exception
"Our results point to a future where we can improve metabolic health without losing muscle mass," said paper co-author and Stockholm University molecular biologist professor Tore Bengtsson in a statement

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