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GLP-1 shortened the cycle length of pacemaker action potentials ( Figure 5AC )
finally, the mice used are all from the standardized UM-HET3 four-way cross which do not have the genetic peculiarities of the vastly more common and severely inbred C57BL/6 strain
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Many in vivo and in vitro studies make use of Ex-4, a well-known orthosteric antagonist for the GLP-1R [27]
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Notably, these neurotoxic effects are rarely seen at doses below 100 mg/day in adults
