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[DOI] [PubMed] [Google Scholar] 555.Liao P., Yang D., Liu D., Zheng Y

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Adipogenic differentiation of thyroid cancer cells through the pax8-ppar fusion protein is regulated by thyroid transcription factor 1 (TTF-1)

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that may help adults and children aged 12 years and older with obesity, or some adults with overweight who also have weight-related medical problems, to help them lose excess body weight and keep the weight off

Further, ~5% of patients are intolerant to metformin 18,20