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3.5 Risk of bias assessment The Cochrane Risk of Bias tool (RoB 2) was used to thoroughly assess the methodological quality of the 40 included RCTs

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In 2014, the FDA and the EMA found no causal association between GLP-1RA and pancreatic adverse events (67)
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Two 16-week phase 1 trials, one in subjects with obesity and another with T2D, shows significant reductions in body weight and HbA1c, respectively (95)
