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Moreover, these analyses have already been done in conventional meta-analyses, showing for SGLT-2 inhibitors the lack of significant difference in the reduced risk of the composite outcome (CV death + HHF) in patients with or without type 2 diabetes or in subjects of 65 years of age or younger vs those older than 65 years of age [13]

Because the utility function is derived from a 5-level EQ-5D (EQ-5D-5L) multivariable model [63] and is BMI-dependent, changes in BMI translate into changes in overall HRQoL over time

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Semaglutide GLP-1 injections have also been shown to lower the risk of a stroke, heart attack, heart or blood vessel disease, or death in patients that are obese or more at risk for these conditions, and those with type 2 diabetes