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The effects of exendin-4 on reward were also diminished by pretreatment with the estrogen receptor--selective antagonist, suggesting that signaling via the estrogen receptor- specifically is necessary for GLP-1R analog's reward-reducing effects (40)

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When asked if she'd return to professional tennis, Williams told TODAY's Savannah Guthrie: "I'm having fun and enjoying life right now." Last fall, she quietly registered with the International Tennis Integrity Agency's drug-testing body, sparking rumors that she was coming out of retirement, which she shut down in December, NBC Sports reported

Perinatal risk factors for childhood obesity and metabolic dysregulation

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