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Meanwhile, risks could still develop with longer term GLP-1 receptor agonist use

4.3 Weight change 4.3.1 Uncontrolled studies While insulin monotherapy causes consistent weight gain, adding GLP-1RA leads to consistent weight loss

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Wollenhaupt-Aguiar B, Kapczinski F, Pfaffenseller B

The pilot study found that GLP-1 agonists reduced monthly migraine days by almost half