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For peptide antigen to induce suppression, we chose only a single I-E d -chain disparity between donor and recipients, leaving untargeted a multitude of other MHC class I and minor antigen differences between the two mouse strains

[17] [18] Several ongoing clinical trials, including the EVOKE and EVOKE+ studies, are investigating whether semaglutide could potentially have beneficial effects in Alzheimer's disease, but results are pending and no cognitive benefits in humans have been established

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Neuroinflammation 138 WinbladB.AmouyelP.AndrieuS.BallardC.BrayneC.BrodatyH.et al (2016)