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The platform offers multiple delivery formats beyond standard injections, including oral dissolving tablets and sublingual drops, which appeals to patients who are needle-averse

These medications include semaglutide (Ozempic for diabetes, Wegovy for obesity), liraglutide (Victoza for diabetes, Saxenda for obesity), dulaglutide (Trulicity, approved only for diabetes), and tirzepatide (Mounjaro for diabetes, Zepbound for obesity), which is a dual GLP-1/GIP receptor agonist

Hall KD, Guo J

-4 DPP-4 -4 .241 GLP-1(936) -

The Phase 2 trial starting dose was 2 mg once weekly by subcutaneous injection, mirroring the initiation approach used with other incretin-based therapies

Further sensitivity analyses showed the absence of pleiotropy ( P pleiotropy =0.899) and heterogeneity ( P heterogeneity =1.000), again demonstrating the robustness of the conclusions