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The rise of GLP-1 medicationssuch as Ozempic and Wegovyis rapidly transforming employer-sponsored health insurance.

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The success of these agents in preclinical models and clinical trials suggests a promising future for multiagonists in the treatment of metabolic diseases, with the most recent glucose-dependent insulinotropic peptide receptor:glucagon-like peptide 1 receptor:glucagon receptor (GIPR:GLP-1R:GCGR) triagonists rivaling the efficacy of bariatric surgery

GLP-1 medications help millions lose weight, but not everyone is a candidate

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