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A small piece of filter paper soaked in a capsaicin solution (33 mM in 10% ethanol, 10% tween80 and 80% saline, Sigma, Saint Louis, MO) was wrapped around the vessels for 10 min

GDF15 provides an endocrine signal of nutritional stress in mice and humans

The gastrointestinal side effects-nausea (44%), diarrhea (30%), and vomiting (25%) are far more commonly reported

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This mechanism helps improve glycaemic control in people with type 2 diabetes

In the 1980s at Mass General, Habener studied the molecular causes of type 2 diabetes and worked to identify the gene for the hormone glucagon, which raises blood sugar levels when they fall too low