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The GLP-1 analogs, semaglutide and liraglutide, delay the progression of atherosclerosis by regulating inflammatory pathways in low-density lipoprotein receptor-deficient (LDLr -/- ) and apolipoprotein E-deficient (ApoE -/- ) mice [16]

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Williams D.L

Lixisenatide (Adlyxin), which is FDA-approved but no longer marketed in the US, has a half-life of about 3 hours

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Warning: Not suitable for pregnant and breastfeeding women and in case of allergy to any of the ingredients

Key Characteristics Medication class GLP-1 & GIP/GLP-1 receptor agonists Active compounds Tirzepatide (Zepbound/Mounjaro-class) Semaglutide (Wegovy-class) Administration Weekly subcutaneous injection self-administered at home