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At standard therapeutic doses, tirzepatide generally produces greater weight loss than semaglutide in head-to-head comparisons

insulin glargine were 1.2 (tirzepatide 5 mg), 2.1 (tirzepatide 10 mg) and 2.0 (tirzepatide 15 mg) ml/min/1.73 m 2 per year, consistent with previous findings and suggesting a dose-dependent benefit [52]

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