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Tirzepatide has demonstrated similar cardiovascular benefits in ongoing trials

Only 4-8% of people discontinue treatment due to these side effects, most find them manageable

He added the group is on track to deliver its first slate of recommendations in June

Reduced rates of acute kidney injury and chronic kidney disease

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome

This is not a reason to start metformin on its own, but it is a relevant consideration if metformin is already part of the clinical conversation
