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Again, not only is there not a reason to believe it will work, theres not a reason to believe that people can stay on the drugs that long

The clinical evidence linking GLP-1 drugs to NAION is significant

Across 5 clinical trials with an exposure time of at least 52 weeks, 4 of 245 subjects (1.6%) were positive for antibodies against setmelanotide

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Front Endocrinol (Lausanne) 14(12):735824 [DOI] [PMC free article] [PubMed] [Google Scholar] 78.Cheng L, Hu Y, Li YY, Cao X, Bai N, Lu TT, Li GQ, Li N, Wang AN, Mao XM (2019) Glucagon-like peptide-1 receptor agonists and risk of bone fracture in patients with type 2 diabetes: A meta-analysis of randomized controlled trials