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Notably, SCFA-mediated GLP-1 release was abolished in Gpr43 -deficient mice, confirming receptor dependency (Psichas et al., 2015)
In contrast, GLP-1RAs provide prolonged systemic effects, making them well-suited for managing chronic conditions like T2D and obesity
Another mechanism by which GLP1 receptor agonists lower blood pressure is through enhancing natriuresis (55)
[DOI] [PubMed] [Google Scholar] 61.Buteau J, Foisy S, Rhodes CJ, et al
MAGIC (Mayo Anesthesia Gastric Imaging Collaborative) Collaborators
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