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Description
The trade-offs: higher cost, less dose flexibility, and dependence on manufacturer supply

These products may be impure, counterfeit, or incorrectly dosed, which can cause serious health problems

If you are currently using an approved weight management medicine and experience concerning symptoms such as severe or persistent abdominal pain, persistent vomiting, a notably rapid heart rate, or signs of an allergic reaction contact your GP promptly or call NHS 111

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For other concerns, it is important not to stop the medication abruptly without medical advice, as this could affect diabetes control or weight management

Moreover, GIP has been found to boost glucose uptake by improving insulin sensitivity in adipocytes (176, 177), while tirzepatide has been demonstrated to enhance insulin sensitivity and promote glucose disposal in white adipose tissue in Glp-1r-null mice (178), further supporting a direct effect of GIP on adipose tissues
