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These may include gastrointestinal symptoms such as reflux, nausea, vomiting, diarrhea, and constipation

Another study, not yet published, is SURMOUNT-OSA, a clinical trial of 52-weeks that examined the efficacy and safety of TZP versus placebo in obese participants and an established OSA diagnosis for treatment of moderate and severe OSA (102)
This initiation precipitates a multitude of alterations in the cellular milieu, notably the augmentation of mitochondrial biogenesis-a mechanism responsible for the genesis of new mitochondria

As more studies are being published, more evidence points to the medications protective effects against developing any AMD in patients who do not have any AMD at baseline
GLP-1RAs act on several of these mechanisms
10.1038/ijo.2013.149 76 le RouxC
