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Experts say we are likely to see continued advances with drugs like semaglutide

Recent studies have revealed that neuronal Glp1r activation in mice is required for the reduction in systemic inflammation through a unique set of neurotransmitter systems 32 and that brainstem neurons can sense peripheral cytokines and exert control over systemic immune responses 33 , suggesting complex neuro-immune communication circuits

As experts have previously told Inverse , GLP-1 agonists also affect appetite neural pathways associated with the reward and pleasure aspects of eating, which is likely how these drugs can have secondary cognitive effects like curbing addictive behaviors

Semaglutide's metabolic effects are largely reversibleappetite signals and gastric emptying return to baseline within weeks of discontinuation

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