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This is done through the upregulation of specific transporters: the facilitated diffusion glucose transporters (GLUTs) superfamily (SLC2A) and sodium-glucose linked transporter (SGLTs) family (SLC5)

Inositol benefits for PCOS include improved insulin sensitivity 19 , fertility and pregnancy outcomes, metabolic health, and inflammation

Rapid-acting insulin doses may also need reduction, especially if you experience hypoglycemic episodes or consistently low readings before meals

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The American Diabetes Association (ADA) and American Association of Clinical Endocrinologists recommend against combination therapy with a DPP4-inhibitor and a GLP-1 RA due to the lack of evidence that this strategy is beneficial