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Mitochondria and anti-oxidants The neuroprotection of GLP-1RAs is attributed to the restoration of mitochondrial function, reduction of oxidative stress, and prevention of subsequent apoptosis
Meaningful metabolic changes require 8-12 weeks of consistent use combined with diet and exercise modifications
GLP-1R trafficking by high content microscopy SNAP/FLAG-hGLP-1R internalisation INS-1 832/3 SNAP/FLAG-hGLP-1R WT or V229A cells were seeded onto poly-L-lysine-coated black, clear bottom 96-well plates
16 This is especially seen in assisted reproductive settings used due to infertility problems stemming from advanced age and poor ovarian reserve, where it can play a role in mitigating metabolic and reproductive disturbances and enhancing the odds of pregnancy post-IVF
45% of Egyptians are obese
