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Lastly, most trials (and observational studies) did not consider duration of diabetes as an eligibility criterion or account for this by subgroup analyses

Treatment with tirzepatide did not increase the odds of hypoglycaemia but was associated with increased incidence of gastrointestinal adverse events, mainly nausea

The most prominent metabolic alterations in HF are a reduction in the utilization of FAO and ATP production (5759)

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Whether Kaiser Permanente covers Mounjaro depends on the specific plan and region, as well as the medical condition its being prescribed for

To decrease the risk of reverse causation bias (ie, that early outcomes would be related to a previous hyperkalemia diagnosis before starting the drug and therefore not related to the treatments under study), we further excluded people who had a hyperkalemia diagnosis in the inpatient or outpatient setting or potassium binder use in the 90 days before cohort entry
