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reported that liraglutide effectively reversed the deleterious effects of insulin overstimulation and attenuated neuronal insulin resistance in the human neuroblastoma cell line SH-SY5Y, which resulted in reductions in -amyloid formation and tau hyperphosphorylation (Jantrapirom et al., 2020)

Your GP can: Assess whether your weight or BMI warrants clinical intervention Refer you to an appropriate NHS weight management service Discuss licensed pharmacological options if clinically indicated Advise on the risks of using topiramate outside its licensed indications In summary, topiramate is not a weight loss pill

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If you have questions about managing your medication or need any more guidance on traveling with GLP-1s, dont hesitate to contact us

doi: 10.1016/S1553-7250(12)38016-1 [DOI] [PubMed] [Google Scholar] 32

Clinical trials demonstrated increased incidence of cholelithiasis (gallstones) and cholecystitis with tirzepatide, likely related to rapid weight loss