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Description
Most people at this point notice subtle appetite changes and perhaps a pound or two of weight loss

Brown, E., Wilding, J

MOTS-c is a potential therapeutic target for multiple aging-related diseases, including neurodegeneration, osteoporosis, cardiovascular disease, atherosclerosis, sarcopenia, type 2 diabetes mellitus, and obesity
others tolerate moderate amounts

Its important action is the stimulation of insulin secretion through binding to GLP-1R on pancreatic cells

D.et al (2015)