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Research shows estrogen and progesterone influence both gastrointestinal motility and glucose metabolism, potentially altering how your body absorbs and responds to GLP-1 therapy during different cycle phases

13 Improved Energy Expenditure GLP-1RAs may increase energy expenditure
This may be due to altered -cell function in diabetic patients, which impairs the efficacy of GLP-1(936)
Zhang WJ, Tan YF, Yue JT, Vranic M, Wojtowicz JM

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[22] reported a weight-independent effect of GIP receptor stimulation on insulin sensitivity
