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How to Reduce Symptoms Start with the lowest dose: gradual dose changes often improve tolerance
The expansion of BMAT under conditions such as caloric restriction may also play a role by altering the bone marrow niche and inhibiting osteoblastogenesis through adipocyte-derived cytokines
Gastrointestinal side effects lead some patients to discontinue treatment, and weight regain after stopping therapy is common
JAMA Cardiology
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But there are crucial pieces of this puzzle that have to be addressed
