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Stem Cells International 2022, 8671482

Furthermore, urothelium from individuals with IC has demonstrated reduced cell proliferation and increased cell permeability (Fiehn and Kim, 2014)

In animal models of diet-induced obesity, diabetes, or alcohol-induced metabolic dysfunctions, scopoletin restored insulin sensitivity, reversed disruptions in circulating lipids, glucose, insulin, and inflammatory cytokines, while also attenuating lipid accumulation and fibrosis in liver, restoring adiponectin levels in white adipose tissue, and reducing oxidative stress in the pancreas (181187)

[DOI] [PubMed] [Google Scholar] 36.Zhou Y., He A., Xu B