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Reference Rosenstock J et al

The effects of liraglutide were evaluated on EAE-induced female Lewis rats [23]

Finally, although genetic manipulation is one of the strengths of preclinical work, it is important to recognize that transgenic manipulations can induce developmental compensations in parallel pathways that can mask the overall effect of loss of the gene on surgical outcome

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Discovery of GLP-1 led to elucidation of their conversion to proglucagon by proprotein convertases such as furin [5,6]

These products were distributed to patients